85. Joanne C. Smith

« 84. John Bryan86. Andrew Alexander » AGE: 50 OCCUPATION: President and CEO, Rehabilitation Institute of Chicago At the helm of the country’s top rehab hospital since 2006, Smith is overseeing plans for a new Streeterville facility—slated to open in 2016 at a projected cost of $450 million—that will increase the institute’s capacity and boost … Read more

33. Dick Durbin

« 32. Larry Goodman34. Rick Bayless » AGE: 67 OCCUPATION: United States senator This amiable successor to Paul Simon is using his clout as majority whip (the Senate’s number two job) to become Illinois’s sugar daddy, securing billions for projects, pork or otherwise. Recently, he helped bring in $1.5 billion for a high-speed rail line … Read more

86. Andrew Alexander

« 85. Joanne C. Smith87. Michelle Boone » AGE: 67 OCCUPATION: Co-owner and CEO, The Second City How do you turn funny into a $35 million empire? Just watch Alexander shuttle between Hollywood, where he hatches film and TV projects, and Chicago, where he keeps a firm grip on TSC’s local comedy productions and 12 … Read more

87. Michelle Boone

« 86. Andrew Alexander88. Michael Pfleger » AGE: 50 OCCUPATION: Commissioner, Department of Cultural Affairs and Special Events, City of Chicago Last June, the mayor crowned her Chicago’s culture czar (a.k.a. the new Lois Weisberg). But with great power comes great responsibility. Will the former Joyce Foundation programming officer succeed in rebooting the city’s Frankendepartment … Read more

88. Michael Pfleger

« 87. Michelle Boone89. Scott Harris » AGE: 62 OCCUPATION: Pastor, St. Sabina Catholic Church Grabbing headlines for his antiviolence rallies and outreach to prostitutes, the controversial Catholic priest and passionate social justice activist often clashes with Cardinal George (No. 18). His South Side parishioners—and the media—love him for it. MORE ON PFLEGER: Father Courage: … Read more

89. Scott Harris

« 88. Michael Pfleger90. Bruce Rauner » AGE: 50 OCCUPATION: Restaurateur Chicago has spoken: It loves Scott Harris. His Francesca restaurant chain has 20 area locations and counting, he recently unveiled the enormous hits Davanti Enoteca and The Purple Pig, and his kingdom—soon to include a pizzeria, a taqueria, and a wine bar—is expanding to … Read more

9. Grant Achatz

« 8. Penny Pritzker10. Eric Lefkofsky » AGE: 37 OCCUPATION: Chef and restaurateur Chicago’s restaurant scene may once have lagged behind the coasts—but not since Achatz vaporized and aromatized his way to the pinnacle of the foodie-verse. You better believe that each time he launches the next Next menu (homage to El Bulli in progress), … Read more

91. Vince Vaughn

« 90. Bruce Rauner92. Devin Hester » AGE: 41 OCCUPATION: Actor and producer When it comes to steering Hollywood projects our way, this bro-comedy star is in a league of his own. Scripts with nary a mention of the Midwest are filmed here after this intensely loyal native son goes to bat for Chicago and … Read more

92. Devin Hester

« 91. Vince Vaughn93. Andrew J. McKenna » AGE: 29 OCCUPATION: Wide receiver, Chicago Bears Already the greatest return man of all time, Hester mesmerizes stadiums of fans, TV audiences, and sportswriters whenever a kickoff is headed his way. What will he do next? We’re tuning in. MORE ON HESTER: You Should Know… Devin Hester … Read more

93. Andrew J. McKenna

« 92. Devin Hester94. Lou Raizin » AGE: 82 OCCUPATION: Chairman, Schwarz Supply Source Mr. Behind-the-Scenes in business and local philanthropy and considered an éminence grise among Chicago dealmakers, McKenna is nonexecutive chairman of the McDonald’s board and on the Aon board at an age when most directors have politely been told to go home. … Read more