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Tony Magee

The Chicago native who led the craft beer charge returned to his roots last year, opening a 250,000-barrel-a-year brewery—the city’s largest—in depressed Douglas Park. Changes to This Story February 23, 2015: An earlier version of this story misstated Lagunitas’s production. It should have read 250,000 barrels a year, not 25,000.

Joanne Smith

The institute’s medical mastermind and chief fundraiser has helped it stay atop U.S. News & World Report’s list of the best rehab centers 24 consecutive years. Now she leads an expansion into a $550 million hospital that will open in 2017.